PO-04-222 OUTFLOW TRACT VERSUS NON-OUTFLOW TRACT VENTRICULAR ARRHYTHMIAS IN ATHLETES: MYOCARDIAL SUBSTRATE AND LONG-TERM CLINICAL OUTCOMES

Outflow tract ventricular arrhythmias (OT-VA) are common in healthy subjects without structural heart disease (SHD), and generally considered benign. However, athlete-specific data on the clinical meaning of different arrhythmia (VA) morphologies scarce. To assess prevalence SHD as well long-term sports medicine outcomes a cohort athletes with OT-VA undergoing comprehensive diagnostic assessment, by comparing them non-outflow VAs (nOT-VA). We conducted multi-center, observational, retrospective study enrolling who were referred because complex (>500 PVCs/24 h, exercise-induced VAs, nonsustained or sustained tachycardia). Athletes categorized into two groups: OT-VA, case monomorphic left bundle branch block inferior axis morphology; nOT-VA, polymorphic right superior/intermediate axis. The co-primary survival free from all-cause death practice at last follow-up. 175 (OT-VA,n=82; nOT-VA,n=93) included present analysis; characteristics resumed Table. Remarkably, signs was higher nOT-VA compared to (Table). A final diagnosis idiopathic VA more and, accordingly, catheter ablation commonly performed former group. Over median follow-up 61(43-85) months, there 2 cardiac arrests 1 appropriate ICD shock, all occurring group vivo evidence for an overall primary outcome event 0 3% groups, respectively (p=0.25). At follow-up, 31 (18%) practiced competitive (OT-VA vs. nOT-VA,p=0.23), while 92 (53%) leisure-time nOT-VA,p=0.91). Our confirm that underlying substrate is lower than major adverse events occurred VAs. Nevertheless, workup liberal use magnetic resonance allowed identification substantial minority clear implications eligibility assessment.